{"id":8089,"date":"2023-06-08T06:30:49","date_gmt":"2023-06-08T10:30:49","guid":{"rendered":"https:\/\/gastropedia.pub\/en\/?p=8089"},"modified":"2023-12-29T16:33:26","modified_gmt":"2023-12-29T21:33:26","slug":"screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer","status":"publish","type":[121],"link":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/","title":{"rendered":"Screening for anal intraepithelial neoplasia and prevention of anal cancer"},"content":{"rendered":"<h2 class=\"wp-block-heading\"><strong>Incidence of anal and anal canal cancer<\/strong><\/h2>\n<p>Squamous cell carcinoma of the anus and anal canal has a low incidence in the general population (1-2\/100,000 people-year). However, when associated with risk factors such as co-infection with HIV, men who have sex with men (MSM), presence of high-grade lesions or carcinoma in the genitals and immunosuppression, this risk can increase considerably:<\/p>\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><a href=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vinicius.jpg\" data-rel=\"penci-gallery-image-content\"  data-rel=\"penci-gallery-image-content\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-5829\" src=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vinicius-1024x720.jpg?v=1684936628\" sizes=\"(max-width: 511px) 100vw, 511px\" srcset=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vinicius-1024x720.jpg?v=1684936628 1024w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vinicius-300x211.jpg?v=1684936628 300w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vinicius-768x540.jpg?v=1684936628 768w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vinicius-585x412.jpg?v=1684936628 585w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vinicius.jpg?v=1684936628 1160w\" alt=\"\" width=\"511\" height=\"359\" \/><\/a><figcaption class=\"wp-element-caption\"><strong>Incidence graph of anal cancer. Clifford et al (1)<\/strong><\/figcaption><\/figure>\n<\/div>\n<p>Anus and anal canal cancer can be screened with a complete proctological examination, with inspection and rectal touch, followed by anoscopy with biopsy in suspicious lesions (3).<\/p>\n<p>High-grade anal intraepithelial lesions (high-grade AIN), as occurs in the cervix, can be identified through exams such as oncotic cytology or genotyping for high-risk oncogenic HPV obtained through the anal smear (<em>Anal-Pap<\/em>).<\/p>\n<p>When these results come altered, the patient should be referred for a high-resolution anoscopy examination or anoscopy with image magnification, which resembles a colposcopy examination of the anus and anal canal region. Through this examination, it is possible to identify lesions suspicious for high-grade AIN, which, when identified through a biopsy, should be treated, through chemical cauterization or electrocautery or with infrared laser (4)<\/p>\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vini1-3.jpg\" data-rel=\"penci-gallery-image-content\"  data-rel=\"penci-gallery-image-content\"><img decoding=\"async\" class=\"wp-image-5835\" src=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vini1-3.jpg\" sizes=\"(max-width: 310px) 100vw, 310px\" srcset=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vini1-3.jpg?v=1684937452 484w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/vini1-3-300x248.jpg?v=1684937452 300w\" alt=\"\" width=\"310\" height=\"256\" \/><\/a><figcaption class=\"wp-element-caption\"><strong>Anal smear (Anal-PAP) for cytology<\/strong><\/figcaption><\/figure>\n<\/div>\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><a href=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/IMG_6175-3.jpg\" data-rel=\"penci-gallery-image-content\"  data-rel=\"penci-gallery-image-content\"><img decoding=\"async\" class=\"wp-image-5837\" src=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/IMG_6175-3-910x1024.jpg?v=1684937589\" sizes=\"(max-width: 314px) 100vw, 314px\" srcset=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/IMG_6175-3-910x1024.jpg?v=1684937589 910w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/IMG_6175-3-267x300.jpg?v=1684937589 267w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/IMG_6175-3-768x864.jpg?v=1684937589 768w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/IMG_6175-3-1170x1316.jpg?v=1684937589 1170w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/IMG_6175-3-585x658.jpg?v=1684937589 585w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/IMG_6175-3.jpg?v=1684937589 1242w\" alt=\"\" width=\"314\" height=\"352\" \/><\/a><figcaption class=\"wp-element-caption\"><strong>High-resolution anoscopy<\/strong><\/figcaption><\/figure>\n<\/div>\n<h2 class=\"wp-block-heading\"><strong>ANCHOR <em>trial<\/em><\/strong><\/h2>\n<ul>\n<li>Until recently, there was not a robust degree of evidence to indicate the screening and treatment of high-grade anal intraepithelial lesions as a method of prevention for anal and anal canal cancer (2).<\/li>\n<li>However, in 2022 the results of the ANCHOR <em>trial<\/em>, (<strong>A<\/strong>nal <strong>C<\/strong>ancer <strong>H<\/strong>SIL <strong>O<\/strong>utcomes <strong>R<\/strong>esearch) (5) a prospective multicenter randomized study that evaluated 4446 people living with HIV who were followed up with cytology exams and high-resolution anoscopy were published in the NEJM.<\/li>\n<li>When high-grade anal intraepithelial lesions (AIN 2 p16+ or AIN3) were identified, the participants were randomized into two groups: one in which these lesions would be treated and another in which these lesions would be followed up every 6 months.<\/li>\n<li>The rate of progression to anal cancer was 53% lower in the treated group than in the group only followed up (p= 0.03).<\/li>\n<\/ul>\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/Anchor-Kepler-Meyer.jpg\" data-rel=\"penci-gallery-image-content\"  data-rel=\"penci-gallery-image-content\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-5838\" src=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/Anchor-Kepler-Meyer.jpg\" sizes=\"(max-width: 512px) 100vw, 512px\" srcset=\"https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/Anchor-Kepler-Meyer.jpg?v=1684937733 792w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/Anchor-Kepler-Meyer-300x193.jpg?v=1684937733 300w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/Anchor-Kepler-Meyer-768x495.jpg?v=1684937733 768w, https:\/\/gastropedia.com.br\/wp-content\/uploads\/2023\/05\/Anchor-Kepler-Meyer-585x377.jpg?v=1684937733 585w\" alt=\"\" width=\"512\" height=\"330\" \/><\/a><figcaption class=\"wp-element-caption\"><strong>Kaplan-Meier curve of anal cancer progression &#8211; ANCHOR trial. Palefsky et al (5)<\/strong><\/figcaption><\/figure>\n<\/div>\n<h2 class=\"wp-block-heading\"><strong>Conclusion<\/strong><\/h2>\n<ul>\n<li>Anus and anal canal cancer is quite rare and should not be screened in the general population.<\/li>\n<li>Its incidence increases considerably in certain populations such as: people living with HIV, men who have sex with men, women with a history of cancer or high-grade lesions in the genitals and diseases or treatments that course with immunosuppression, which justifies screening in these groups.<\/li>\n<li>The identification and treatment of high-grade anal intraepithelial lesions in people living with HIV has proven effective in preventing anal and anal canal cancer.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\"><strong>References<\/strong><\/h2>\n<ol>\n<li>Clifford, Gary M., et al. &#8220;A meta-analysis of anal cancer incidence by risk group: toward a unified anal cancer risk scale.&#8221; <em>International journal of cancer<\/em> 148.1 (2021): 38-47.<\/li>\n<li>Stewart, David B., et al. &#8220;The American Society of Colon and Rectal Surgeons clinical practice guidelines for anal squamous cell cancers (revised 2018).&#8221; <em>Diseases of the Colon &amp; Rectum<\/em> 61.7 (2018): 755-774.<\/li>\n<li>Hillman, Richard John, et al. &#8220;International Anal Neoplasia Society guidelines for the practice of digital anal rectal examination.&#8221; <em>Journal of lower genital tract disease<\/em> 23.2 (2019): 138-146.<\/li>\n<li>Hillman, Richard John, et al. &#8220;2016 IANS international guidelines for practice standards in the detection of anal cancer precursors.&#8221; <em>Journal of lower genital tract disease<\/em> 20.4 (2016): 283-291<\/li>\n<li>Palefsky, Joel M., et al. &#8220;Treatment of anal high-grade squamous intraepithelial lesions to prevent anal cancer.&#8221; <em>New England Journal of Medicine<\/em> 386.24 (2022): 2273-2282.<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\"><strong>How to cite this article<\/strong><\/h2>\n<p class=\"has-background\" style=\"background-color: #ccd9d9;\">Ribeiro VL. Screening of anal intraepithelial neoplasia and prevention of anal cancer. Gastropedia 2023, vol. 1. Available at: <a href=\"https:\/\/gastropedia.com.br\/?p=5828\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/gastropedia.com.br\/sem-categoria\/rastreamento-de-neoplasia-intrapeitelial-anal-e-prevencao-de-cancer-de-anus\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Incidence of anal and anal canal cancer Squamous cell carcinoma of the anus and anal canal has a low incidence in the general population (1-2\/100,000 people-year). However, when associated with&hellip;<\/p>\n","protected":false},"author":5682,"featured_media":8062,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[26,24],"tags":[],"volume":[57],"year":[137],"class_list":["post-8089","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-colorectal","category-surgery","type-general-topics","volume-volume-i","year-137"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.2 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Screening for anal intraepithelial neoplasia and prevention of anal cancer - Gastropedia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Screening for anal intraepithelial neoplasia and prevention of anal cancer\" \/>\n<meta property=\"og:description\" content=\"Incidence of anal and anal canal cancer Squamous cell carcinoma of the anus and anal canal has a low incidence in the general population (1-2\/100,000 people-year). However, when associated with&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"Gastropedia\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-08T10:30:49+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-12-29T21:33:26+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/gastropedia.pub\/en\/wp-content\/uploads\/2023\/11\/vini1-3.jpg?v=1701258065\" \/>\n\t<meta property=\"og:image:width\" content=\"484\" \/>\n\t<meta property=\"og:image:height\" content=\"400\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Vin\u00edcius Lacerda Ribeiro\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Vin\u00edcius Lacerda Ribeiro\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/\"},\"author\":{\"name\":\"Vin\u00edcius Lacerda Ribeiro\",\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/#\\\/schema\\\/person\\\/0435c7bfeaf8ea779be7aadc1da50442\"},\"headline\":\"Screening for anal intraepithelial neoplasia and prevention of anal cancer\",\"datePublished\":\"2023-06-08T10:30:49+00:00\",\"dateModified\":\"2023-12-29T21:33:26+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/\"},\"wordCount\":592,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/wp-content\\\/uploads\\\/2023\\\/11\\\/vini1-3.jpg?v=1701258065\",\"articleSection\":[\"Colorectal\",\"Surgery\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/\",\"url\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/\",\"name\":\"Screening for anal intraepithelial neoplasia and prevention of anal cancer - Gastropedia\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/wp-content\\\/uploads\\\/2023\\\/11\\\/vini1-3.jpg?v=1701258065\",\"datePublished\":\"2023-06-08T10:30:49+00:00\",\"dateModified\":\"2023-12-29T21:33:26+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/#\\\/schema\\\/person\\\/0435c7bfeaf8ea779be7aadc1da50442\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/#primaryimage\",\"url\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/wp-content\\\/uploads\\\/2023\\\/11\\\/vini1-3.jpg?v=1701258065\",\"contentUrl\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/wp-content\\\/uploads\\\/2023\\\/11\\\/vini1-3.jpg?v=1701258065\",\"width\":484,\"height\":400},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/surgery\\\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Screening for anal intraepithelial neoplasia and prevention of anal cancer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/\",\"name\":\"Gastropedia\",\"description\":\"Easy medical updates for digestive health practitioners.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/#\\\/schema\\\/person\\\/0435c7bfeaf8ea779be7aadc1da50442\",\"name\":\"Vin\u00edcius Lacerda Ribeiro\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/?d=identicon&amp;s=96\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/?d=identicon&amp;s=96\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/?d=identicon&amp;s=96\",\"caption\":\"Vin\u00edcius Lacerda Ribeiro\"},\"description\":\"M\u00e9dico Cirurgi\u00e3o do Aparelho Digestivo. Assistente do Ambulat\u00f3rio de Doen\u00e7as Infecciosas do \u00c2nus e do Reto do Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo\",\"url\":\"https:\\\/\\\/gastropedia.pub\\\/en\\\/author\\\/vinicius-lacerda\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Screening for anal intraepithelial neoplasia and prevention of anal cancer - Gastropedia","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/","og_locale":"en_US","og_type":"article","og_title":"Screening for anal intraepithelial neoplasia and prevention of anal cancer","og_description":"Incidence of anal and anal canal cancer Squamous cell carcinoma of the anus and anal canal has a low incidence in the general population (1-2\/100,000 people-year). However, when associated with&hellip;","og_url":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/","og_site_name":"Gastropedia","article_published_time":"2023-06-08T10:30:49+00:00","article_modified_time":"2023-12-29T21:33:26+00:00","og_image":[{"width":484,"height":400,"url":"https:\/\/gastropedia.pub\/en\/wp-content\/uploads\/2023\/11\/vini1-3.jpg?v=1701258065","type":"image\/jpeg"}],"author":"Vin\u00edcius Lacerda Ribeiro","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Vin\u00edcius Lacerda Ribeiro","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/#article","isPartOf":{"@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/"},"author":{"name":"Vin\u00edcius Lacerda Ribeiro","@id":"https:\/\/gastropedia.pub\/en\/#\/schema\/person\/0435c7bfeaf8ea779be7aadc1da50442"},"headline":"Screening for anal intraepithelial neoplasia and prevention of anal cancer","datePublished":"2023-06-08T10:30:49+00:00","dateModified":"2023-12-29T21:33:26+00:00","mainEntityOfPage":{"@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/"},"wordCount":592,"commentCount":0,"image":{"@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/gastropedia.pub\/en\/wp-content\/uploads\/2023\/11\/vini1-3.jpg?v=1701258065","articleSection":["Colorectal","Surgery"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/","url":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/","name":"Screening for anal intraepithelial neoplasia and prevention of anal cancer - Gastropedia","isPartOf":{"@id":"https:\/\/gastropedia.pub\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/#primaryimage"},"image":{"@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/gastropedia.pub\/en\/wp-content\/uploads\/2023\/11\/vini1-3.jpg?v=1701258065","datePublished":"2023-06-08T10:30:49+00:00","dateModified":"2023-12-29T21:33:26+00:00","author":{"@id":"https:\/\/gastropedia.pub\/en\/#\/schema\/person\/0435c7bfeaf8ea779be7aadc1da50442"},"breadcrumb":{"@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/#primaryimage","url":"https:\/\/gastropedia.pub\/en\/wp-content\/uploads\/2023\/11\/vini1-3.jpg?v=1701258065","contentUrl":"https:\/\/gastropedia.pub\/en\/wp-content\/uploads\/2023\/11\/vini1-3.jpg?v=1701258065","width":484,"height":400},{"@type":"BreadcrumbList","@id":"https:\/\/gastropedia.pub\/en\/surgery\/screening-for-anal-intraepithelial-neoplasia-and-prevention-of-anal-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/gastropedia.pub\/en\/"},{"@type":"ListItem","position":2,"name":"Screening for anal intraepithelial neoplasia and prevention of anal cancer"}]},{"@type":"WebSite","@id":"https:\/\/gastropedia.pub\/en\/#website","url":"https:\/\/gastropedia.pub\/en\/","name":"Gastropedia","description":"Easy medical updates for digestive health practitioners.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/gastropedia.pub\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/gastropedia.pub\/en\/#\/schema\/person\/0435c7bfeaf8ea779be7aadc1da50442","name":"Vin\u00edcius Lacerda Ribeiro","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/?d=identicon&amp;s=96","url":"https:\/\/secure.gravatar.com\/avatar\/?d=identicon&amp;s=96","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/?d=identicon&amp;s=96","caption":"Vin\u00edcius Lacerda Ribeiro"},"description":"M\u00e9dico Cirurgi\u00e3o do Aparelho Digestivo. Assistente do Ambulat\u00f3rio de Doen\u00e7as Infecciosas do \u00c2nus e do Reto do Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","url":"https:\/\/gastropedia.pub\/en\/author\/vinicius-lacerda\/"}]}},"_links":{"self":[{"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/posts\/8089","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/users\/5682"}],"replies":[{"embeddable":true,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/comments?post=8089"}],"version-history":[{"count":1,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/posts\/8089\/revisions"}],"predecessor-version":[{"id":8310,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/posts\/8089\/revisions\/8310"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/media\/8062"}],"wp:attachment":[{"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/media?parent=8089"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/categories?post=8089"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/tags?post=8089"},{"taxonomy":"type","embeddable":true,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/type?post=8089"},{"taxonomy":"volume","embeddable":true,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/volume?post=8089"},{"taxonomy":"year","embeddable":true,"href":"https:\/\/gastropedia.pub\/en\/wp-json\/wp\/v2\/year?post=8089"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}